Gale W. Starkey

Advisor
St. Louis, Missouri

Gale Starkey is a non-legal scientific advisor and patent agent for Spencer Fane's Life Sciences Practice focusing on patent preparation and prosecution, intellectual property due diligence, patent opinion analysis, and specializing in chemistry, pharmaceuticals, and biotechnology.

Dr. Starkey earned a B.A. in Chemistry from Illinois Wesleyan University and a Ph.D. in Organic Chemistry at Washington University in St. Louis followed by postdoctoral research in drug discovery at Monsanto. He taught chemistry at Southern Illinois University Edwardsville as well as consulted for several St. Louis area biotechnology companies. Prior to joining Spe...

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Areas of Emphasis

Pharmaceuticals, Formulation, Medicinal Chemistry, Organic Synthesis, Asymmetric Catalysis, Organometallic Chemistry, Palladium Chemistry, Phosphorus Chemistry, Amino Acid Synthesis, Peptide Synthesis, Process Chemistry, High Throughput Screening (HTS), Structure Activity Relationships (SAR), Intellectual Property, Patents, Patent Searching, Freedom-to-Operate Analysis, Due Diligence, and Competitive Intelligence.

Presentations

“Sifting Through HTS Output to Find the Right Lead Series: Fresh Approaches to a Well-Known Problem” 10th Annual Drug Discovery and Technology Conference, Boston, Massachusetts, August 2005

“Polymer-Supported IIDQ: A Reagent for High-Throughput Synthesis” 223rd American Chemical Society National Meeting, Orlando, April 2002

“A Chemical Library Synthesis and Purification Strategy for the Mitsunobu Reaction” 216th American Chemical Society National Meeting, Boston, Massachusetts, August 1998

"Palladium Catalyzed Synthesis of Phosphine Amino Acids and Peptides;" 209th American Chemical Society National Meeting, Anaheim, California, April 1994

Publications

"Synthesis of Phosphine Containing Amino Acids: Utilization of Peptide Synthesis in Ligand Design", Anton Agarkov, Scott Greenfield, Dejian Xie, Robert Pawlick, Gale Starkey, and Scott R. Gilbertson, Biopolymers, 2006, 84, 48-73

"Palladium-catalyzed Synthesis of Vinyl Phosphines from Ketones", Scott R. Gilbertson, Zice Fu, and Gale W. Starkey, Tetrahedron Letters, 1999, 40, 8509

“Chemically-Tagged Mitsunobu Reagents for Use in Solution-Phase Chemical Library Synthesis”, Gale W. Starkey, John J. Parlow, and Daniel L. Flynn Bioorganic and Medicinal Chemistry Letters, 1998, 8, 17, 2385-2390

"Palladium Catalyzed Synthesis of Phosphine Amino Acids", Gale W. Starkey and Scott R. Gilbertson Journal of Org...

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*Neither the Supreme Courts nor the Bars of Missouri, Kansas or Nebraska review or approve certifying organizations or specialist designations.